Upneeq (oxymetazoline hydrochloride ophthalmic solution, 0.1%) is the first and only FDA-approved, prescription eye drop used to treat acquired blepharoptosis (low-lying or droopy eyelids) in adults. It works by stimulating the Müller’s muscle to contract, lifting the upper eyelid in as little as 15 minutes to 2 hours, with effects lasting up to 6 hours.
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